Comfort Inn - Wytheville Virginia HOTEL PHOTO / INFO / WEBSITE / MAP SEND TO A FRIEND HOTEL WEBSITE ADD TO FAVORITES Comfort Inn - Wytheville Virginia HOTEL ADDRESS: 315 Holston Rd., Wytheville, Virginia, 24382 Description: Nestled in beautiful Wytheville, VA. Just south of I-77/81 junctions. Antique shopping. Scrooges restaurant next door. Wytheville Virginia Hotel Photo: URL: http://www.choicehotels.com/ires/hotel/VA422?clientid=SKqvHhFptuSz Hotel Website: Comfort Inn - Wytheville Virginia Area Map: Comfort Inn - Wytheville Virginia Hotel Area Map

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